Anti-endothelial cell antibodies mediate enhanced leukocyte adhesion to cytokine-activated endothelial cells through a novel mechanism requiring cooperation between FcγRIIa and CXCR1/2. Running Title: Anti-endothelial antibodies and leukocyte adhesion
نویسندگان
چکیده
Oliver J. Florey, Michael Johns, Olubukola O. Esho, Justin C. Mason, Dorian O. Haskard BHF Cardiovascular Medicine, National Heart and Lung Institute Imperial College London, Hammersmith Hospital Du Cane Road, London W12 ONN United Kingdom Authors contributions: OJF helped design the study and performed the research; MJ and OOE helped perform the research, JCM helped design the research, and DOH designed the research and wrote the paper. Funding: This work was funded by grants from the Wellcome Trust, British Heart Foundation and Arthritis Research Campaign Correspondence to: Dorian O. Haskard, BHF Cardiovascular Medicine Unit, National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, Du Cane Road, London W12 ONN. Tel: (0)208-383-3064; Fax: (0)208-383-1640; [email protected]
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Antiendothelial cell antibodies mediate enhanced leukocyte adhesion to cytokine-activated endothelial cells through a novel mechanism requiring cooperation between Fc{gamma}RIIa and CXCR1/2.
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